{"id":94,"date":"2014-09-12T07:11:51","date_gmt":"2014-09-12T11:11:51","guid":{"rendered":"http:\/\/blogs.kzoo.edu\/mwollenb\/?page_id=94"},"modified":"2022-07-21T09:55:51","modified_gmt":"2022-07-21T13:55:51","slug":"researchaims","status":"publish","type":"page","link":"http:\/\/blogs.kzoo.edu\/mwollenb\/welcome\/research\/researchaims\/","title":{"rendered":"Specific Aims"},"content":{"rendered":"\n<p>Currently, we are focused on two areas of&nbsp;<em>Photorhabdus&nbsp;<\/em>research.<br><a name=\"one\"><\/a><\/p>\n\n\n\n<h2 id=\"specific-aim-1\">Specific Aim 1<\/h2>\n\n\n\n<p>Why do they glow &amp; how is light production regulated in these bacteria (Fig. 1)?<\/p>\n\n\n\n<p><img loading=\"lazy\" class=\" wp-image-507\" src=\"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-content\/uploads\/sites\/6\/2014\/09\/uxOperonsVfVcPl.png\" alt=\"LuxOperonsVfVcPl\" width=\"614\" height=\"382\"><br><strong>Figure 1<\/strong>. Cartoon of the <em>lux&nbsp;<\/em>operon (grey box) in&nbsp;<em>P. luminescens&nbsp;<\/em>and two marine bacteria (<em>Vibrio fischeri&nbsp;<\/em>and&nbsp;<em>Vibrio cholerae<\/em>); identified and putative regulators of the <em>lux <\/em>operon are represented by green arrows.<br><a name=\"two\"><\/a><\/p>\n\n\n\n<h2 id=\"specific-aim-2\">Specific Aim 2<\/h2>\n\n\n\n<p>What is the microbial ecology (Fig. 2) of the nematode and insect larva hosts?<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img src=\"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-content\/uploads\/sites\/6\/2014\/09\/6STypes.png\" alt=\"16STypes\" class=\"wp-image-515\" \/><\/figure>\n\n\n\n<p><strong>Figure 2<\/strong>. <em>Photorhabdus&nbsp;<\/em>infection greatly decreases the microbial taxa present in the host. Major bacterial taxa\/OTUs identified by 16S rDNA sequencing are represented by distinct colors in each histogram above. Uninfected larvae host a relatively diverse community in contrast to dead larvae infected by&nbsp;<em>Photorhabdus&nbsp;<\/em>and its nematode host.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Currently, we are focused on two areas of&nbsp;Photorhabdus&nbsp;research. Specific Aim 1 Why do they glow &amp; how is light production regulated in these bacteria (Fig. 1)? Figure 1. Cartoon of the lux&nbsp;operon (grey box) in&nbsp;P. luminescens&nbsp;and two marine bacteria (Vibrio fischeri&nbsp;and&nbsp;Vibrio cholerae); identified and putative regulators of the lux operon are represented by green arrows. [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":71,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/pages\/94"}],"collection":[{"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/comments?post=94"}],"version-history":[{"count":14,"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/pages\/94\/revisions"}],"predecessor-version":[{"id":465,"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/pages\/94\/revisions\/465"}],"up":[{"embeddable":true,"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/pages\/71"}],"wp:attachment":[{"href":"http:\/\/blogs.kzoo.edu\/mwollenb\/wp-json\/wp\/v2\/media?parent=94"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}